Gepefrine

Gepefrine
Clinical data
ATC code	C01CA15 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name (±)-3-(2-aminopropyl)phenol;
CAS Number	1075-61-2 ; S-form: 18840-47-6 ;
PubChem CID	219105;
DrugBank	DB13703 ;
ChemSpider	189921 ;
UNII	L9JB0763SW; S-form: V51RRX51VH ;
KEGG	D07150 ;
ChEMBL	ChEMBL2105064 ;
ECHA InfoCard	100.012.779
Chemical and physical data
Formula	C9H13NO
Molar mass	151.209 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES OC1=CC(C[C@H](C)N)=CC=C1;
	InChI InChI=1S/C9H13NO/c1-7(10)5-8-3-2-4-9(11)6-8/h2-4,6-7,11H,5,10H2,1H3/t7-/m0/s1 ; Key:WTDGMHYYGNJEKQ-ZETCQYMHSA-N ;
	(verify)

Gepefrine (INN; trade names Pressionorm and Wintonin), also known as 3-hydroxyamphetamine, meta-hydroxyamphetamine,^[1] and α-methyl-meta-tyramine, is an antihypotensive or sympathomimetic agent of the amphetamine family that is marketed in certain European countries.^[2]^[3]

It is a known metabolite of amphetamine in rats.^[1]

References

^ ^a ^b Jonsson J (October 1977). "Identification of metahydroxyamphetamine as a metabolite of amphetamine in the rat". Research Communications in Chemical Pathology and Pharmacology. 18 (2): 189–99. PMID 918344.
^ Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. p. 487. ISBN 978-3-88763-075-1. Retrieved 24 April 2012.
^ Macdonald F (1997). Dictionary of Pharmacological Agents. CRC Press. p. 127. ISBN 978-0-412-46630-4. Retrieved 24 April 2012.

[pmid918344-1] Jonsson J (October 1977). "Identification of metahydroxyamphetamine as a metabolite of amphetamine in the rat". Research Communications in Chemical Pathology and Pharmacology. 18 (2): 189–99. PMID 918344.

[Index_Nominum_2000:_International_Drug_Directory-2] Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. p. 487. ISBN 978-3-88763-075-1. Retrieved 24 April 2012.

[Macdonald1997-3] Macdonald F (1997). Dictionary of Pharmacological Agents. CRC Press. p. 127. ISBN 978-0-412-46630-4. Retrieved 24 April 2012.

[1]

[2]

[3]

Clinical data

ATC code	C01CA15 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name (±)-3-(2-aminopropyl)phenol
CAS Number	1075-61-2 S-form: 18840-47-6
PubChem CID	219105
DrugBank	DB13703
ChemSpider	189921
UNII	L9JB0763SW S-form: V51RRX51VH
KEGG	D07150
ChEMBL	ChEMBL2105064
ECHA InfoCard	100.012.779
Chemical and physical data
Formula	C₉H₁₃NO
Molar mass	151.209 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES OC1=CC(C[C@H](C)N)=CC=C1
InChI InChI=1S/C9H13NO/c1-7(10)5-8-3-2-4-9(11)6-8/h2-4,6-7,11H,5,10H2,1H3/t7-/m0/s1 Key:WTDGMHYYGNJEKQ-ZETCQYMHSA-N
(verify)

Gepefrine

See also

References