Streptolysins are two hemolyticexotoxins from Streptococcus.[1][2] Types include streptolysin O (SLO; slo), which is oxygen-labile, and streptolysin S (SLS; sagA), which is oxygen-stable.[3]
SLO is part of the thiol-activated cytolysin family.[4] It is hemolytically active only in a reversibly reduced state. It is antigenic, so its antibody antistreptolysin O can be detected in an antistreptolysin O titre.
SLS is stable in the presense of oxygen. It is not antigenic due to its small size. It is sometimes considered a bacteriocin due to similarities in the synthesis pathway.[5]
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