Tramazoline

Tramazoline
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	R01AA09 (WHO) ;
Identifiers
	IUPAC name N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine;
CAS Number	1082-57-1 ;
PubChem CID	5524;
ChemSpider	5323 ;
UNII	SLE31693IV;
KEGG	D08624 ;
ChEMBL	ChEMBL32573 ;
CompTox Dashboard (EPA)	DTXSID5046936 ;
ECHA InfoCard	100.012.823
Chemical and physical data
Formula	C13H17N3
Molar mass	215.300 g·mol−1
	(verify)

Tramazoline is a chemical that is used in the form of tramazoline hydrochloride in nasal decongestant preparations.^[1] It is an α-adrenergic receptor agonist that inhibits secretion of nasal mucus.

It was patented in 1961 and came into medical use in 1962.^[2]

Brand names

Australia

Spray-Tish^[3]
Rhinaspray

Austria

Rhinorix

Belgium

Rhinospray

Bulgaria

Muconasal Plus

Czech Republic

Muconasal Plus

Germany

Biciron
Ellatun
Rhinospray

Italy

Rinogutt
Fexallegra® nasale (Tramazoline + Chlorpheniramine, 1 mg/ml + 3.55 mg/ml)

Romania

Muconasal Plus (older)
Muconasal (newer)

Russia

Adrianol (tramazoline + phenylephrine)
Lasolvan Rhino

Spain and Portugal

Rhinospray

Slovakia

Muconasal Plus

Ukraine

Lasorin

US

trama ^[4]

References

^ Boehringer Ingelheim. "Spray-Tish Consumer Information". Consumer Medicines Information. MyDr.com.au. Retrieved 16 April 2011.
^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 552. ISBN 9783527607495.
^ "Spray-Tish". Consumer Information. Retrieved 16 April 2011.
^ "Trama". Consumer Information. Retrieved 21 December 2019.

[1] Boehringer Ingelheim. "Spray-Tish Consumer Information". Consumer Medicines Information. MyDr.com.au. Retrieved 16 April 2011.

[Fis2006-2] Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 552. ISBN 9783527607495.

[3] "Spray-Tish". Consumer Information. Retrieved 16 April 2011.

[4] "Trama". Consumer Information. Retrieved 21 December 2019.

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