Aspartame-acesulfame salt

Aspartame-acesulfame salt^[1]
Names
	IUPAC name [2-carboxyl-1-(N-(1-methoxycarbonyl-2-phenyl)ethylcarbamoyl)]ethanaminium 6-methyl-4-oxo-1,2,3-oxathiazin-3-ide-2,2-dioxide
	Other names Salt of Aspartame-acesulfame Twinsweet
Identifiers
CAS Number	106372-55-8 ;
3D model (JSmol)	Interactive image;
ChemSpider	9147744 ;
E number	E962 (glazing agents, ...)
PubChem CID	10972537;
UNII	IFE6C6BS24 ;
CompTox Dashboard (EPA)	DTXSID30909991 ;
	InChI InChI=1S/C14H18N2O5.C4H5NO4S/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18;1-3-2-4(6)5-10(7,8)9-3/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18);2H,1H3,(H,5,6)/t10-,11-;/m0./s1 Key: KVHQNWGLVVERFR-ACMTZBLWSA-N ; InChI=1/C14H18N2O5.C4H5NO4S/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18;1-3-2-4(6)5-10(7,8)9-3/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18);2H,1H3,(H,5,6)/t10-,11-;/m0./s1 Key: KVHQNWGLVVERFR-ACMTZBLWBH;
	SMILES O=S1(=O)O/C(=C\C(=O)[NH2+]1)C.[O-]C(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)Cc1ccccc1;
Properties
Chemical formula	C18H23O9N3S
Molar mass	457.46
Appearance	white crystalline powder
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Aspartame-acesulfame salt is an artificial sweetener marketed under the name Twinsweet. It is produced by soaking a 2-1 mixture of aspartame and acesulfame potassium in an acidic solution and allowing it to crystallize; moisture and potassium are removed during this process. It is approximately 350 times as sweet as sucrose. It has been given the E number E962.^[2]

History

Aspartame-acesulfame salt was invented in 1995 by sweetener expert Dr John Fry^[3] while working for The Holland Sweetener Company (HSC), a subsidiary of DSM |DSM. HSC marketed it with the name Twinsweet. It was approved for use as an artificial sweetener in the European Parliament and Council Directive 94/35 EC as amended by Directive 2003/ 115/ EC in 2003. In North America it falls under the same regulations as aspartame and acesulfame-K, and is also approved for use in China, Russia, Hong-Kong, Australia and New Zealand.

In December 2006 HSC ceased all of its aspartame operations, citing a glut in the market driving prices below profitable values.^[4] The rights to aspartame-acesulfame are now owned by The NutraSweet Company Inc who have continued to market the sweetener successfully in the USA and EU.

References

^ "Archived copy" (PDF). Archived from the original (PDF) on 2008-09-10. Retrieved 2007-10-21.
^ "Holland Sweetener rolls out Twinsweet". BakeryAndSnacks.com. William Reed Business Media. November 19, 2003. Retrieved July 29, 2011.
^ US Patent 5827562, Sweetener Salts
^ "DSM pulls out of aspartame market". FoodNavigator. 2006-03-30.

External links

Media related to Aspartame-acesulfame salt at Wikimedia Commons
Holland Sweetener Company

[1] "Archived copy" (PDF). Archived from the original (PDF) on 2008-09-10. Retrieved 2007-10-21.

[2] "Holland Sweetener rolls out Twinsweet". BakeryAndSnacks.com. William Reed Business Media. November 19, 2003. Retrieved July 29, 2011.

[3] US Patent 5827562, Sweetener Salts

[4] "DSM pulls out of aspartame market". FoodNavigator. 2006-03-30.

[1]

[2]

[3]

[4]

Names


IUPAC name [2-carboxyl-1-(N-(1-methoxycarbonyl-2-phenyl)ethylcarbamoyl)]ethanaminium 6-methyl-4-oxo-1,2,3-oxathiazin-3-ide-2,2-dioxide
Other names Salt of Aspartame-acesulfame Twinsweet
Identifiers
CAS Number	106372-55-8
3D model (JSmol)	Interactive image
ChemSpider	9147744
E number	E962 (glazing agents, ...)
PubChem CID	10972537
UNII	IFE6C6BS24
CompTox Dashboard (EPA)	DTXSID30909991
InChI InChI=1S/C14H18N2O5.C4H5NO4S/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18;1-3-2-4(6)5-10(7,8)9-3/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18);2H,1H3,(H,5,6)/t10-,11-;/m0./s1 Key: KVHQNWGLVVERFR-ACMTZBLWSA-N InChI=1/C14H18N2O5.C4H5NO4S/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18;1-3-2-4(6)5-10(7,8)9-3/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18);2H,1H3,(H,5,6)/t10-,11-;/m0./s1 Key: KVHQNWGLVVERFR-ACMTZBLWBH
SMILES O=S1(=O)O/C(=C\C(=O)[NH2+]1)C.[O-]C(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)Cc1ccccc1
Properties
Chemical formula	C₁₈H₂₃O₉N₃S
Molar mass	457.46
Appearance	white crystalline powder
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).