Propylamine

Propylamine
Names
	Preferred IUPAC name Propan-1-amine
	Other names Propylamine
Identifiers
CAS Number	107-10-8 ;
3D model (JSmol)	Interactive image;
Beilstein Reference	1098243
ChEBI	CHEBI:39870 ;
ChEMBL	ChEMBL14409 ;
ChemSpider	7564 ;
ECHA InfoCard	100.003.149
EC Number	203-462-3;
Gmelin Reference	1529
PubChem CID	7852;
RTECS number	UH9100000;
UNII	I76F18D635 ;
UN number	1277
CompTox Dashboard (EPA)	DTXSID6021878 ;
	InChI InChI=1S/C3H9N/c1-2-3-4/h2-4H2,1H3 Key: WGYKZJWCGVVSQN-UHFFFAOYSA-N ;
	SMILES CCCN;
Properties
Chemical formula	C3H9N
Molar mass	59.112 g·mol−1
Appearance	Colorless liquid
Odor	fishy, ammoniacal
Density	0.719 g mL−1
Melting point	−83.00 °C; −117.40 °F; 190.15 K
Boiling point	47 to 51 °C; 116 to 124 °F; 320 to 324 K
Solubility in water	Miscible
log P	0.547
Vapor pressure	33.01 kPa (at 20 °C)
Henry's law; constant (kH)	660 μmol Pa−1 kg−1
Acidity (pKa)	10.71
Refractive index (nD)	1.388
Thermochemistry
Heat capacity (C)	162.51 J K−1 mol−1
Std molar; entropy (So298)	227.44 J K−1 mol−1
Std enthalpy of; formation (ΔfH⦵298)	−101.9–−101.1 kJ mol−1
Std enthalpy of; combustion (ΔcH⦵298)	−2.368–−2.362 MJ mol−1
Hazards
GHS pictograms
GHS Signal word	Danger
GHS hazard statements	H225, H302, H311, H314, H331
GHS precautionary statements	P210, P261, P280, P305+351+338, P310
Flash point	−30 °C (−22 °F; 243 K)
Explosive limits	2–10.4%
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	370 mg kg−1 (oral, rat); 402.6 mg kg−1 (dermal, rabbit);
Related compounds
Related alkanamines	Ethylamine; Ethylenediamine; Isopropylamine; 1,2-Diaminopropane; 1,3-Diaminopropane; Isobutylamine; tert-Butylamine; n-Butylamine; sec-Butylamine; Putrescine;
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Propylamine, also known as n-propylamine, is an amine with the chemical formula CH₃(CH₂)₂NH₂.^[1] It is a colorless volatile liquid.^[2]

Propylamine is a weak base. Its K_b (base dissociation constant) is 4.7 × 10⁻⁴.

Preparation

Propyl amine hydrochloride can be prepared by reacting 1-propanol with ammonium chloride at high temperature and pressure using a Lewis acid catalyst such as ferric chloride.

References

^ https://pubchem.ncbi.nlm.nih.gov/compound/Propylamine
^ Karsten Eller, Erhard Henkes, Roland Rossbacher, Hartmut Höke "Amines, Aliphatic" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2005. doi:10.1002/14356007.a02_001

External links

International Chemical Safety Card

[PubChem-1] ttps://pubchem.ncbi.nlm.nih.gov/compound/Propylamine

[Ullmann-2] Karsten Eller, Erhard Henkes, Roland Rossbacher, Hartmut Höke "Amines, Aliphatic" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2005. doi:10.1002/14356007.a02_001

[1]

[2]

Names


Preferred IUPAC name Propan-1-amine
Other names Propylamine
Identifiers
CAS Number	107-10-8
3D model (JSmol)	Interactive image
Beilstein Reference	1098243
ChEBI	CHEBI:39870
ChEMBL	ChEMBL14409
ChemSpider	7564
ECHA InfoCard	100.003.149
EC Number	203-462-3
Gmelin Reference	1529
PubChem CID	7852
RTECS number	UH9100000
UNII	I76F18D635
UN number	1277
CompTox Dashboard (EPA)	DTXSID6021878
InChI InChI=1S/C3H9N/c1-2-3-4/h2-4H2,1H3 Key: WGYKZJWCGVVSQN-UHFFFAOYSA-N
SMILES CCCN
Properties
Chemical formula	C₃H₉N
Molar mass	59.112 g·mol⁻¹
Appearance	Colorless liquid
Odor	fishy, ammoniacal
Density	0.719 g mL⁻¹
Melting point	−83.00 °C; −117.40 °F; 190.15 K
Boiling point	47 to 51 °C; 116 to 124 °F; 320 to 324 K
Solubility in water	Miscible
log P	0.547
Vapor pressure	33.01 kPa (at 20 °C)
Henry's law constant (k_H)	660 μmol Pa⁻¹ kg⁻¹
Acidity (pK_a)	10.71
Refractive index (n_D)	1.388
Thermochemistry
Heat capacity (C)	162.51 J K⁻¹ mol⁻¹
Std molar entropy (S^o₂₉₈)	227.44 J K⁻¹ mol⁻¹
Std enthalpy of formation (Δ_fH^⦵₂₉₈)	−101.9–−101.1 kJ mol⁻¹
Std enthalpy of combustion (Δ_cH^⦵₂₉₈)	−2.368–−2.362 MJ mol⁻¹
Hazards
GHS pictograms
GHS Signal word	Danger
GHS hazard statements	H225, H302, H311, H314, H331
GHS precautionary statements	P210, P261, P280, P305+351+338, P310
Flash point	−30 °C (−22 °F; 243 K)
Explosive limits	2–10.4%
Lethal dose or concentration (LD, LC):
LD₅₀ (median dose)	370 mg kg⁻¹ (oral, rat) 402.6 mg kg⁻¹ (dermal, rabbit)
Related compounds
Related alkanamines	Ethylamine Ethylenediamine Isopropylamine 1,2-Diaminopropane 1,3-Diaminopropane Isobutylamine tert-Butylamine n-Butylamine sec-Butylamine Putrescine
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).