Ensulizole

Ensulizole
Names
	IUPAC name 2-Phenyl-3H-benzimidazole-5-sulfonic acid
Identifiers
CAS Number	27503-81-7 ;
3D model (JSmol)	Interactive image;
ChemSpider	31267 ;
ECHA InfoCard	100.044.078
KEGG	D10005 ;
PubChem CID	33919;
UNII	9YQ9DI1W42 ;
CompTox Dashboard (EPA)	DTXSID3038852 ;
	InChI InChI=1S/C13H10N2O3S/c16-19(17,18)10-6-7-11-12(8-10)15-13(14-11)9-4-2-1-3-5-9/h1-8H,(H,14,15)(H,16,17,18) Key: UVCJGUGAGLDPAA-UHFFFAOYSA-N ; InChI=1/C13H10N2O3S/c16-19(17,18)10-6-7-11-12(8-10)15-13(14-11)9-4-2-1-3-5-9/h1-8H,(H,14,15)(H,16,17,18) Key: UVCJGUGAGLDPAA-UHFFFAOYAY;
	SMILES O=S(=O)(O)c3ccc2[nH]c(c1ccccc1)nc2c3;
Properties
Chemical formula	C13H10N2O3S
Molar mass	274.29 g·mol−1
Hazards
Safety data sheet	Cole Parmer Material Safety Data Sheet
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Ensulizole (INN;^[1] also known as phenylbenzimidazole sulfonic acid) is a common sunscreen agent. In 1999, the United States Food and Drug Administration regulated that the name ensulizole be used on sunscreen labels in the United States. Ensulizole is primarily a UVB protecting agent providing only minimal UVA protection. The scope of UVB is 290 to 340 nanometers whereas the UVA range is 320 to 400 nanometers.^[2] For better UVA protection, it must be paired with avobenzone, titanium dioxide, or zinc oxide; outside of the United States it can also be paired with a UV absorber of the Tinosorb or Mexoryl types. Because ensulizole is water-soluble, it has the characteristic of feeling lighter on skin. As such, it is often used in sunscreen lotions or moisturizers whose aesthetic goal is a non-greasy finish.^[3] The free acid is poorly soluble in water, so it is only used as its soluble salts.^[4]

References

^ "International non-proprietary name". Medinet. Retrieved 6 May 2016.
^ http://www.uspdqi.org/pubs/monographs/sunscreen_agents.pdf
^ eMedicine - Sunscreens and Photoprotection : Article by Stanley B Levy
^ http://www.merck.de/servlet/PB/menu/1254590/index.html

External links

[1] "International non-proprietary name". Medinet. Retrieved 6 May 2016.

[2] ttp://www.uspdqi.org/pubs/monographs/sunscreen_agents.pdf

[3] Medicine - Sunscreens and Photoprotection : Article by Stanley B Levy

[4] ttp://www.merck.de/servlet/PB/menu/1254590/index.html

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Names


IUPAC name 2-Phenyl-3H-benzimidazole-5-sulfonic acid
Identifiers
CAS Number	27503-81-7
3D model (JSmol)	Interactive image
ChemSpider	31267
ECHA InfoCard	100.044.078
KEGG	D10005
PubChem CID	33919
UNII	9YQ9DI1W42
CompTox Dashboard (EPA)	DTXSID3038852
InChI InChI=1S/C13H10N2O3S/c16-19(17,18)10-6-7-11-12(8-10)15-13(14-11)9-4-2-1-3-5-9/h1-8H,(H,14,15)(H,16,17,18) Key: UVCJGUGAGLDPAA-UHFFFAOYSA-N InChI=1/C13H10N2O3S/c16-19(17,18)10-6-7-11-12(8-10)15-13(14-11)9-4-2-1-3-5-9/h1-8H,(H,14,15)(H,16,17,18) Key: UVCJGUGAGLDPAA-UHFFFAOYAY
SMILES O=S(=O)(O)c3ccc2[nH]c(c1ccccc1)nc2c3
Properties
Chemical formula	C₁₃H₁₀N₂O₃S
Molar mass	274.29 g·mol⁻¹
Hazards
Safety data sheet	Cole Parmer Material Safety Data Sheet
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).