Lithium citrate

Lithium citrate
Names
	Other names Trilithium citrate; trilithium 2-hydroxypropane-1,2,3-tricarboxylate
Identifiers
CAS Number	919-16-4 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL1201170 ;
ChemSpider	12932 ;
ECHA InfoCard	100.011.860
PubChem CID	13520;
RTECS number	TZ8616000;
UNII	3655633623 ;
CompTox Dashboard (EPA)	DTXSID70883185 ;
	InChI InChI=1S/C6H8O7.3Li/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3+1/p-3 Key: WJSIUCDMWSDDCE-UHFFFAOYSA-K ; InChI=1/C6H8O7.3Li/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3+1/p-3 Key: WJSIUCDMWSDDCE-DFZHHIFOAV;
	SMILES [Li+].[Li+].[Li+].O=C([O-])CC(O)(C([O-])=O)CC(=O)[O-];
Properties
Chemical formula	Li3C6H5O7
Molar mass	209.923 g mol−1
Appearance	Odorless white powder
Melting point	decomposes at 105 °C (221 °F; 378 K)
Hazards
Main hazards	Toxic
R-phrases (outdated)	R22 R36 R37 R38
Flash point	N/A
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Lithium citrate (Li₃C₆H₅O₇) is a chemical compound of lithium and citrate that is used as a mood stabilizer in psychiatric treatment of manic states and bipolar disorder.^[1]^[2] There is extensive pharmacology of lithium, the active component of this salt.

Lithia water contains various lithium salts, including the citrate. An early version of Coca-Cola available in pharmacies' soda fountains called Lithia Coke was a mixture of Coca-Cola syrup and lithia water. The soft drink 7Up was originally named "Bib-Label Lithiated Lemon-Lime Soda" when it was formulated in 1929 because it contained lithium citrate. The beverage was a patent medicine marketed as a cure for hangover. Lithium citrate was removed from 7Up in 1948.^[3]

References

^ Medication description
^ Medical use Archived 2006-06-15 at the Wayback Machine
^ Gielen, Marcel; Edward R. T. Tiekink (2005). Metallotherapeutic drugs and metal-based diagnostic agents: The use of metals in medicine. John Wiley and Sons. p. 3. ISBN 0-470-86403-6.

[1] Medication description

[2] Medical use Archived 2006-06-15 at the Wayback Machine

[gielen_3-3] Gielen, Marcel; Edward R. T. Tiekink (2005). Metallotherapeutic drugs and metal-based diagnostic agents: The use of metals in medicine. John Wiley and Sons. p. 3. ISBN 0-470-86403-6.

[1]

[2]

[3]

Names

Other names Trilithium citrate trilithium 2-hydroxypropane-1,2,3-tricarboxylate
Identifiers
CAS Number	919-16-4
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL1201170
ChemSpider	12932
ECHA InfoCard	100.011.860
PubChem CID	13520
RTECS number	TZ8616000
UNII	3655633623
CompTox Dashboard (EPA)	DTXSID70883185
InChI InChI=1S/C6H8O7.3Li/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3+1/p-3 Key: WJSIUCDMWSDDCE-UHFFFAOYSA-K InChI=1/C6H8O7.3Li/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3+1/p-3 Key: WJSIUCDMWSDDCE-DFZHHIFOAV
SMILES [Li+].[Li+].[Li+].O=C([O-])CC(O)(C([O-])=O)CC(=O)[O-]
Properties
Chemical formula	Li₃C₆H₅O₇
Molar mass	209.923 g mol⁻¹
Appearance	Odorless white powder
Melting point	decomposes at 105 °C (221 °F; 378 K)
Hazards
Main hazards	Toxic
R-phrases (outdated)	R22 R36 R37 R38
Flash point	N/A
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).