The following highways are numbered 2. For roads numbered A2, see list of A2 roads. For roads numbered B2, see list of B2 roads. For roads numbered M2, see list of M2 roads. For roads numbered N2, see list of N2 roads.
International
Asian Highway 2, an international road from Indonesia to Iran
E2 European route E2
E002 European route E002
Trans-Sahara Highway
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Albania
SH-2 Highway in Albania from Tirana to Durrës.
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Argentina
Buenos Aires Provincial Route 2
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Australia
New South Wales
M2 Hills Motorway- Lane Cove Tunnel
Windsor Road (Sydney)
Gold Coast Highway (Queensland, New South Wales)
Windsor Road (Sydney)Northern Territory
(future 
)Namatjira Drive
Queensland
-
- Ipswich Motorway (Brisbane)
- Warrego Highway (Brisbane)
- Logan Motorway (Brisbane)
- Gateway Motorway (Brisbane)
- Warrego (
Toowoomba Bypass), Landsborough, and Barkly Highways (Queensland) 
Warrego and Mitchell Highway- Gold Coast Highway (Queensland, New South Wales)
Brisbane
Toowoomba Bypass), 
BrisbaneSouth Australia
-
- Southern Expressway
- North-South Motorway
- Northern Expressway
Tasmania
- Bass Highway, Tasmania
Victoria
- Tullamarine Freeway (Melbourne)
Western Australia
- State Route 2 (Western Australia) – Mitchell Freeway, Kwinana Freeway, and Forrest Highway
Austria
Süd Autobahn
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Bangladesh
- N2 - Dhaka–Sylhet Highway
Belarus
M2 highway (Belarus)
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Belgium
R2 road (Belgium)
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Bulgaria
Републикански път I-2/Route 2 (I-2/E70)
Автомагистрала „Хемус“ (A2/E73/E83/E772)
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Burma
- National Highway 2 (Burma)
Cambodia
Canada
Alberta Highway 2 (including the Queen Elizabeth II Highway)
British Columbia Highway 2
Manitoba Highway 2.svg.png)
New Brunswick Route 2 (part of the Trans-Canada Highway)
Newfoundland and Labrador Route 2
Northwest Territories Highway 2
Nova Scotia Trunk 2
Ontario Highway 2 (almost entirely removed from the network)
Prince Edward Island Route 2
Quebec Route 2 (former).svg.png)
Saskatchewan Highway 2
Yukon Highway 2
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China
G2 Expressway
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Congo, Democratic Republic of the
- National Road No. 2 (Democratic Republic of the Congo)
Costa Rica
National Route 2
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Czech Republic
D2 from Brno to Bratislava in Slovakia
I/2 Highway (in Czech)
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Djibouti
RN-2 (Djibouti)
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Finland
Finnish national road 2- Åland Islands Highway 2
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France
Germany
Bundesautobahn 2
Bundesstraße 2
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Greece
Εθνική Οδός 2 (EO2)
Εγνατία Οδός (A2/E90)
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Hong Kong
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Hungary
_Otszogletu_kek_tabla.svg.png)
M2 expressway (Hungary)_Otszogletu_zold_tabla.svg.png)
Main road 2 (Hungary)
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India
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2
National Highway 2 (India)
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2
State Highway 2 (Rajasthan)
2
State Highway 2 (Andhra Pradesh)
2
State Highway 2 (West Bengal)
Indonesia
Indonesian National Route 2
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Iran
Freeway 2 (Iran)
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Iraq
Highway 2 (Iraq)
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Ireland
M2 motorway (Republic of Ireland)
N2 road (Ireland)
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Israel
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Japan
National Route 2.png)
San'yō Expressway .jpg)
Chūgoku Expressway- Kanmon Bridge
Route 2 (Shuto Expressway) in Tokyo
Route 2 (Nagoya Expressway)
Route 2 (Hanshin Expressway) in Osaka
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Korea, South
National Route 2
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Malaysia
Mexico
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Moldova
National Road 2 (R2) 
Magistrala 2 (M2/E584) is a national road with highway status. This route leaves Chișinău, via Orhei and the route arrives at Soroca, on the border with Ukraine
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Netherlands
Rijksweg 2
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New Zealand
New Zealand State Highway 2
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Pakistan
M-2 motorway (Pakistan)
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Paraguay
National Route 2 (Paraguay)
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Peru
Peru Highway 2
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Philippines
- C-2 Circumferential Road 2
- R-2 Radial Road 2
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N2 highway (Philippines).svg.png)
E2 expressway (Philippines)
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Poland
National road 2 (DK2)
Motorway of Freedom (A2/E30)
expressway S2, Southern Warsaw Bypass
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Romania
National Road 2 (DN2/E58/E60/E85/E583) 
DN2A
DN2B
Autostrada Soarelui (A2/E81)
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Russia
M2 highway (Russia)
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Senegal
- N2 road (Senegal)
Sri Lanka
- A2 Galle Road
- E02 Colombo Inter-provincial Orbital Router
Taiwan
Freeway 2 (Taiwan)
Provincial Highway 2 (Taiwan)
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Thailand
Thailand Route 2 (Mittraphap Road)
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Turkey
O-2, a motorway in Turkey as the outer half ring road in Istanbul.
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United Kingdom
M2 motorway (Great Britain)- A2 road (England)
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United States
Interstate 2
Interstate A-2 (Alaska; unsigned)
Interstate H-2 (Hawaii)
U.S. Route 2 
U.S. Route 2N (former)
U.S. Route 2S (former)
New England Interstate Route 2 (former)
Alabama State Route 2
Alaska Route 2
Arkansas Highway 2 (former)
California State Route 2
Colorado State Highway 2
Connecticut Route 2
Delaware Route 2
Florida State Road 2 
County Road 2 (Nassau County, Florida)
County Road 2 (Okaloosa County, Florida) 
County Road 2B (Okaloosa County, Florida)
County Road 2 (Walton County, Florida)
Georgia State Route 2
Illinois Route 2
Indiana State Road 2
Iowa Highway 2
K-2 (Kansas highway)
Kentucky Route 2
Louisiana Highway 2 .svg.png)
Louisiana State Route 2 (former)
Maryland Route 2
Massachusetts Route 2
County Road 2 (Goodhue County, Minnesota) 
County Road 2 (Hennepin County, Minnesota)
County Road 2 (Pine County, Minnesota)
County Road 2 (Scott County, Minnesota)
County Road 2 (Washington County, Minnesota)
- Mississippi Highway 2
Missouri Route 2 .svg.png)
Missouri Route 2 (1922) (former)
Montana Highway 2
Nebraska Highway 2 
Nebraska Spur 2B
Nebraska Recreation Road 2D
Nevada State Route 2 (former) 
Nevada State Route 2B (former)
Nevada State Route 2C (former)
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New Jersey Route 2 (former) .svg.png)
New Jersey Route 2N (former)
County Route 2 (Monmouth County, New Jersey)
New Mexico State Road 2
New York State Route 2 - County Route 2 (Allegany County, New York)
- County Route 2 (Chemung County, New York)
- County Route 2 (Chenango County, New York)
County Route 2 (Clinton County, New York)- County Route 2 (Columbia County, New York)
- County Route 2 (Delaware County, New York)
County Route 2 (Dutchess County, New York)
County Route 2 (Erie County, New York)
County Route 2 (Essex County, New York)
County Route 2 (Franklin County, New York)- County Route 2 (Genesee County, New York)
- County Route 2 (Lewis County, New York)
- County Route 2 (Madison County, New York)
- County Route 2 (Monroe County, New York)
County Route 2 (Nassau County, New York)- County Route 2 (Niagara County, New York)
- County Route 2 (Oneida County, New York)
- County Route 2 (Onondaga County, New York)
- County Route 2 (Ontario County, New York)
- County Route 2 (Oswego County, New York)
County Route 2 (Rensselaer County, New York)- County Route 2 (Steuben County, New York)
County Route 2 (Suffolk County, New York)
County Route 2 (Washington County, New York)
County Route 2 (Yates County, New York)
North Carolina Highway 2
Ohio State Route 2
Oklahoma State Highway 2
Oregon Route 2 (former).svg.jpg)
Pennsylvania Route 2 (former)
Rhode Island Route 2
South Carolina Highway 2
Tennessee State Route 2
Texas State Highway 2 (former) 
Texas State Highway Loop 2
Farm to Market Road 2
Texas Park Road 2
Texas Recreational Road 2
Utah State Route 2 (former)
Vermont Route 2B
Virginia State Route 2
Washington State Highway 2 (former)
West Virginia Route 2
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Territories
Guam Highway 2
Interstate PR-2 (unsigned)
Puerto Rico Highway 2 
Puerto Rico Highway 2R
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Uruguay
Route 2 Grito de Asencio
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