HOT-7

HOT-7
Names
	IUPAC name N-[2-(2,5-Dimethoxy-4-propylsulfanyl-phenyl)-ethyl]-hydroxylamine
	Other names 2-[4-(Propylthio)-2,5-dimethoxyphenyl]ethanaminol
Identifiers
CAS Number	207740-39-4 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL127582 ;
ChemSpider	21106321 ;
PubChem CID	44350017;
CompTox Dashboard (EPA)	DTXSID90658372 ;
	InChI InChI=1S/C13H21NO3S/c1-4-7-18-13-9-11(16-2)10(5-6-14-15)8-12(13)17-3/h8-9,14-15H,4-7H2,1-3H3 Key: ASTNLROMDNGJLS-UHFFFAOYSA-N ; InChI=1/C13H21NO3S/c1-4-7-18-13-9-11(16-2)10(5-6-14-15)8-12(13)17-3/h8-9,14-15H,4-7H2,1-3H3 Key: ASTNLROMDNGJLS-UHFFFAOYAX;
	SMILES COc1cc(SCCC)c(cc1CCNO)OC;
Properties
Chemical formula	C13H21NO3S
Molar mass	271.374 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

HOT-7, or 2,5-dimethoxy-4-(β-propylthio)-N-hydroxyphenethylamine, is a psychedelic phenethylamine of the 2C family. It was presumably first synthesized by Alexander Shulgin and reported in his book, PiHKAL.^[1]

Chemistry

HOT-7's full chemical name is 2-[4-(2-propyl thio)-2,5-dimethoxy phenyl–N–hydroxyethanamine. It has structural properties similar to 2C-T-7 and to other drugs in the HOT- series, with the most closely related compounds being HOT-2 and HOT-17.

General information

The dosage range of HOT-7 is typically 15-25 mg and its duration is approximately 6–8 hours according to Shulgin.^[1] HOT-7 produces closed-eye and open-eye visuals. It also induces a feeling similar to that of being drunk.

Legality

United Kingdom

This substance is a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act.^[2]

References

^ ^a ^b PiHKAL #88 HOT-7
^ "UK Misuse of Drugs act 2001 Amendment summary". Isomer Design. Retrieved 12 March 2014.

[PiHKAL-1] PiHKAL #88 HOT-7

[2] "UK Misuse of Drugs act 2001 Amendment summary". Isomer Design. Retrieved 12 March 2014.

[1]

[2]