2-Phosphoglyceric acid

2-Phosphoglyceric acid

Names
IUPAC name 3-hydroxy-2-phosphonooxypropanoic acid
Other names 2PG
Identifiers
CAS Number	2553-59-5
3D model (JSmol)	Interactive image Interactive image
ChEBI	CHEBI:24344
ChemSpider	58
PubChem CID	59
CompTox Dashboard (EPA)	DTXSID20948430
InChI InChI=1S/C3H7O7P/c4-1-2(3(5)6)10-11(7,8)9/h2,4H,1H2,(H,5,6)(H2,7,8,9) Key: GXIURPTVHJPJLF-UHFFFAOYSA-N InChI=1/C3H7O7P/c4-1-2(3(5)6)10-11(7,8)9/h2,4H,1H2,(H,5,6)(H2,7,8,9) Key: GXIURPTVHJPJLF-UHFFFAOYAQ
SMILES C(C(C(=O)O)OP(=O)(O)O)O O=P(O)(O)OC(C(=O)O)CO
Properties
Chemical formula	C3H7O7P
Molar mass	186.06 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

2-Phosphoglyceric acid (2PG), or 2-phosphoglycerate, is a glyceric acid which serves as the substrate in the ninth step of glycolysis. It is catalyzed by enolase into phosphoenolpyruvate (PEP), the penultimate step in the conversion of glucose to pyruvate.

In glycolysis

3-phospho-D-glycerate	Phosphoglyceromutase		2-phospho-D-glycerate	Enolase		phosphoenolpyruvate
					H2O
					H2O
	Phosphoglyceromutase			Enolase

Compound C00197 at KEGG Pathway Database. Enzyme 5.4.2.1 at KEGG Pathway Database. Compound C00631 at KEGG Pathway Database. Enzyme 4.2.1.11 at KEGG Pathway Database. Compound C00074 at KEGG Pathway Database.

Click on genes, proteins and metabolites below to link to respective articles.^{[§ 1]}

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|{{{bSize}}}px|alt=Glycolysis and Gluconeogenesis edit]]

Glycolysis and Gluconeogenesis edit

1. ^ The interactive pathway map can be edited at WikiPathways: "GlycolysisGluconeogenesis_WP534".

See also

• 3-Phosphoglyceric acid

References

Glycolysis metabolic pathway

Glucose Hexokinase ATP ADP Glucose 6-phosphate Glucose-6-phosphate isomerase Fructose 6-phosphate Phosphofructokinase-1 ATP ADP Fructose 1,6-bisphosphate Fructose-bisphosphate aldolase Dihydroxyacetone phosphate + + Glyceraldehyde 3-phosphate Triosephosphate isomerase 2 × Glyceraldehyde 3-phosphate 2 ×  Glyceraldehyde-3-phosphate dehydrogenase NAD++ Pi NADH + H+ NAD++ Pi NADH + H+ 2 × 1,3-Bisphosphoglycerate 2 ×  Phosphoglycerate kinase ADP ATP ADP ATP 2 × 3-Phosphoglycerate 2 ×  Phosphoglycerate mutase 2 × 2-Phosphoglycerate 2 ×  Phosphopyruvate hydratase (enolase) H2O H2O 2 × Phosphoenolpyruvate 2 ×  Pyruvate kinase ADP ATP 2 × Pyruvate 2 ×