Duff may refer to:
People
- Duff (surname)
- Duff (given name)
- William "Duff" Armstrong (1833–1899), American soldier successfully defended by Abraham Lincoln against the charge of murder
- Duff Goldman (born 1974), star of Food Network's reality show Ace of Cakes
- Michael "Duff" McKagan (born 1964), bassist of Velvet Revolver and former bassist of Guns N' Roses
- Karen Duffy, an actress, model, and former MTV VJ once known as "Duff"
Places
- Duff, Indiana, United States, an unincorporated community
- Duff, Nebraska, United States, an unincorporated community
- Duff, Tennessee, United States, an unincorporated community
- Duff, Saskatchewan, Canada, a village
- Duff Hill, a mountain in County Wicklow, Ireland
- Duff River, a river in County Sligo, Ireland
- Duff Islands in the Solomon Islands, Pacific Ocean
- Duff Peak, Victoria Land, Antarctica
- Duff Point, Greenwich Island, Antarctica
Arts and entertainment
- The DUFF (novel), by Kody Keplinger
- The DUFF, a 2015 film based on the Keplinger novel
- Duff Beer, a fictional brand of beer on The Simpsons
- Elmyra Duff, a fictional character on Tiny Toon
Other uses
- Duff (food), a Bahamian dish
- Duff, another name for plant litter, plant material that has fallen to the ground
- Duff, slang term for buttocks
- Plum duff, a pudding of medieval origin
- Duff baronets, three titles in the Baronetage of the United Kingdom
- HMS Duff, more than one British ship of the Royal Navy
- Duff (1794 ship)
- Duff House, Banff, Scotland
- The Down Under Fan Fund
- Duff, an Indian frame drum of Persian origin
See also
- Duff reaction, a formylation reaction used in organic chemistry
- Duff's (disambiguation)
- DUF (disambiguation)