CAST may refer to:
Medicine
- Cardiac Arrhythmia Suppression Trial, a heart study in the 1980s
- Childhood-autism spectrum test, formerly the Childhood Asperger Syndrome Test
- Chronic addiction substitution treatment, a policy adopted in Vancouver Canada to reduce the harms of drug prohibition
Organizations
- CAST (company), a software intelligence company
- Canadian Air-Sea Transportable Brigade Group, a former organization in the Canadian military
- Centre for Analysis of Strategies and Technologies, a Russian non-governmental organization which conducts research on arms trade and defense trends
- Carolina Actors Studio Theatre, a theater company in Charlotte, North Carolina
- China Academy of Space Technology
- China Association for Science and Technology
- Coalition to Abolish Slavery and Trafficking, a Los Angeles-based anti-human trafficking organization
- College of Arts, Science and Technology, former name of the University of Technology, Jamaica
- Curriculum Advice and Support Team, former name of the Scottish Further Education Unit
Technology
- CAST tool, a program for testing software
- CERN Axion Solar Telescope, an experiment in astroparticle physics to search for axions from the Sun
- Computer-aided simple triage, computerized methods or systems that assist physicians
Other
- CAST (gene), which encodes the protein calpastatin
- CAST (race), a fictional race of androids in the Phantasy Star series of video games