Aloxiprin

Aloxiprin
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	B01AC15 (WHO) N02BA02 (WHO);
Identifiers
	IUPAC name aluminum 2-acetyloxybenzoate hydroxide;
CAS Number	9014-67-9;
PubChem CID	3032790;
ChemSpider	2297682 ;
UNII	6QT214X4XU;
KEGG	D07421 ;
CompTox Dashboard (EPA)	DTXSID80889395 ;
ECHA InfoCard	100.041.481
Chemical and physical data
Formula	C18H15AlO9
Molar mass	402.288 g·mol−1
3D model (JSmol)	Interactive image; Interactive image;
	SMILES [Al+3].O=C(Oc1ccccc1C([O-])=O)C.[OH-].[O-]C(=O)c1ccccc1OC(=O)C; ; CC(=O)Oc0ccccc0C(=O)O[Al](O)OC(=O)c1ccccc1OC(=O)C;
	InChI InChI=1S/2C9H8O4.Al.H2O/c21-6(10)13-8-5-3-2-4-7(8)9(11)12;;/h22-5H,1H3,(H,11,12);;1H2/q;;+3;/p-3 ; Key:MANKSFVECICGLK-UHFFFAOYSA-K ;
	(verify)

Aloxiprin (or aluminium acetylsalicylate) is a medical drug used for the treatment of pain and inflammation associated with muscular skeletal and joint disorders.^[1] It is used for its properties as an anti-inflammatory, antipyretic and analgesic drug.^[1] It is a chemical compound of aluminium hydroxide and aspirin.^[2]^[3]

Alternative names and combinations

Palaprin Forte.^[4]
Askit Powders - A powder combination of aspirin, aloxiprin and caffeine.^[5]

Contraindications

People with allergies to salicylates.
People with gastrointestinal ulcers.
People with liver or kidney damage.
Pregnant women in the 3rd trimester.
Women who are breastfeeding.
Use with other salicylates.
Use with NSAIDs.

References

^ ^a ^b MIMS. "Aloxiprin". MIMS. Retrieved 16 April 2011.
^ Encarta. "Aloxiprin". Encarta. Retrieved 16 April 2011.
^ CUMMINGS AJ, MARTIN BK, WIGGINS LF (1963). "In vitro and in vivo properties of aloxiprin: a new aluminium derivative of acetylsalicylic acid". J. Pharm. Pharmacol. 15: 56–62. doi:10.1111/j.2042-7158.1963.tb12743.x. PMID 14024235. S2CID 33366977.
^ Geller J (1968). "A comparative trial of aloxiprin ('Palaprin Forte') and phenylbutazone ('Butazolidin')". The British Journal of Clinical Practice. 22 (9): 392–4. PMID 4876729.
^ Net Doctor UK. "Askit Powders". Treatments for joint, muscle and bone conditions. Retrieved 16 April 2011.

External links

CTD's Aloxiprin page from the Comparative Toxicogenomics Database

[mimsonline-1] MIMS. "Aloxiprin". MIMS. Retrieved 16 April 2011.

[2] Encarta. "Aloxiprin". Encarta. Retrieved 16 April 2011.

[pmid14024235-3] CUMMINGS AJ, MARTIN BK, WIGGINS LF (1963). "In vitro and in vivo properties of aloxiprin: a new aluminium derivative of acetylsalicylic acid". J. Pharm. Pharmacol. 15: 56–62. doi:10.1111/j.2042-7158.1963.tb12743.x. PMID 14024235. S2CID 33366977.

[pmid4876729-4] Geller J (1968). "A comparative trial of aloxiprin ('Palaprin Forte') and phenylbutazone ('Butazolidin')". The British Journal of Clinical Practice. 22 (9): 392–4. PMID 4876729.

[5] Net Doctor UK. "Askit Powders". Treatments for joint, muscle and bone conditions. Retrieved 16 April 2011.

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