SSB may refer to:
Organizations
- Scandinavian School of Brussels
- Social Security Board (disambiguation)
- Societas Sanctae Birgittae, the Society of Saint Bridget
- Society of the Sisters of Bethany, an Anglican order of sisters
- Städtische Strassenbahn Bern, a former public transport operator in Switzerland
- Statistics Norway (Statistisk sentralbyrå), a Norwegian government statistics bureau
- Stuttgarter Straßenbahnen, a public transport operator in Germany
- Sustainable South Bronx, an environmental justice organization
- Swedish School Beijing
Military
- Sashastra Seema Bal, an Indian paramilitary force, formerly called Special Service Bureau
- Secret Service Bureau, of the United Kingdom, now called the Secret Intelligence Service
- Services Selection Board, for the selection of candidates in officer cadre of Indian Armed Forces
- Special Service Battalion, a South African military unit
- Strategic Support Branch, a U.S Department of Defense intelligence agency
Science and technology
- Secure Scuttlebutt
- Single-sideband modulation, in radio technology
- Single-stranded binding protein
- Single-strand break, a break in only one of the two strands on DNA
- Site-specific browser, for an intranet or the Internet
- Sjogren syndrome antigen B, a human gene
- Speculative Store Bypass, a hardware security flaw affecting many processors
- Spontaneous symmetry breaking, in physics
- Stabilized soil block, a type of compressed earth block, a building material
Entertainment
- Super Smash Bros., a fighting game series featuring characters from various video game franchises, primarily Nintendo focused
- Super Smash Bros. (video game), the first game in the series
- Swet Shop Boys, a hip hop group
- Sonic Soldier Borgman, a Japanese animated television series
Other uses
- Ship Submersible Ballistic, a submarine
- Standard Southern British, a name for a variety of English