| Retrovirus direct repeat 1 (dr1) | |
|---|---|
) Predicted secondary structure and sequence conservation of Retro_dr1 | |
| Identifiers | |
| Symbol | Retro_dr1 |
| Rfam | RF00214 |
| Other data | |
| RNA type | Cis-reg |
| Domain(s) | Viruses |
| SO | SO:0000233 |
| PDB structures | PDBe |
The direct repeat 1 (dr1) element is an RNA element commonly found in the 3' UTR of Avian sarcoma, Rous sarcoma and Avian leukosis viruses (Alpharetroviruses and Avian type C retroviruses). dr1 is required for efficient viral replication and is thought to be involved in genomic RNA packaging although this may not be its only role.[1]
References
- ^ Aschoff JM, Foster D, Coffin JM (September 1999). "Point mutations in the avian sarcoma/leukosis virus 3' untranslated region result in a packaging defect". Journal of Virology. 73 (9): 7421–7429. doi:10.1128/JVI.73.9.7421-7429.1999. PMC 104269. PMID 10438832.