R-406A is a refrigerant invented by George H Goble. It is a mixture of three components chlorodifluoromethane (R-22), isobutane (R-600a) and chlorodifluoroethane (R-142b) in the ratio 55/4/41.
This refrigerant was designed as a drop-in replacement for R-12 which is compatible with the typical mineral oil lubricants used in R-12 systems. Since it is a zeotropic mixture, it has a range of boiling points which may increase the effectiveness of the heat transfer elements in refrigeration equipment.
Because it contains R-22, its future is limited due to eventual phase-out of this refrigerant.