Morales is a Spanish surname. Notable people with the surname include:
- Alfredo Morales (born 1990), footballer
- Amado Morales (born 1947), Puerto Rican javelin thrower
- Bartolomé Morales (born 1737), Spanish officer and Florida colonial official
- Camop Elias Delgado Morales (1934-1986), Colombian spree killer
- Carlos Adrián Morales, Mexican football (soccer) player
- Carlos Luis Morales, Ecuadorian football (soccer) goalkeeper
- Carlos Morales Santos, Paraguayan football (soccer) player
- Carlos Morales Troncoso, Dominican politician, current foreign minister
- Carlos Morales (American soccer) (born 1982), Puerto Rican football (soccer) player
- Christina Morales, American politician
- Cristina Morales (born 1993), Spanish kickboxer
- Daniel Morales (swimmer) (born 1977), Spanish former swimmer
- Daniel Morales (footballer) (born 1975), former Brazilian footballer
- Dan Morales (born 1956), American politician from Texas
- David Morales (musician) (born 1961), New York-based American DJ and music producer
- David Sánchez Morales (1925–1978), CIA operative
- Dianne Morales (born 1967), American non-profit executive and political candidate
- Enrique Martín Morales, known as Ricky Martin, Grammy Award Winning Puerto Rican pop singer
- Eduardo Morales Miranda, Chilean physician and founder of Universidad Austral de Chile
- Erik Morales (born 1976), Mexican professional boxer
- Esai Morales (born 1962), Puerto Rican actor
- Evo Morales (born 1959), President of Bolivia
- Fernando Morales (volleyball) (born 1982), Puerto Rican volleyball player
- Florencio Morales Ramos (1915–1989), Puerto Rican singer, trovador and composer
- Francisco Morales (born 1971), Argentine judoka
- Frank Morales (born 1949), New York City-based American priest and journalist
- Franklin Morales (born 1986), Venezuelan baseball player
- Franklin E. Morales (1884–1962), American diplomat
- Jacobo Morales (born 1934), Puerto Rican actor
- Javier Morales (born 1980), Argentine football (soccer) player
- Jimmy Morales, President of Guatemala
- Juan Bautista Morales (c. 1597–1664), Spanish Dominican missionary
- José Morales (designated hitter) (born 1944), American baseball player
- Kendrys Morales (born 1983), Cuban baseball player
- Leonardo Morales (Scouting)
- Luis Morales (athlete) (born 1964), Puerto Rican track and field sprinter
- Manolo Rivera Morales (1934–1996), Puerto Rican sportscaster
- Manuel Morales (basketball) (born 1987), Peruvian basketball player
- Marco Morales (American football), American football player
- Mario Morales (born 1960), Puerto Rican basketball player
- Mark Morales (aka Prince Markie Dee), American dance music producer
- Memo Morales (1937–2017), Venezuelan singer
- Natalie Morales (journalist), American journalist for NBC
- Natalie Morales (actress), an American actress
- Pablo Morales (born 1962) American Olympic swimmer, Gold and Silver medalist
- Pablo Morales Pérez (1905–1969), Venezuelan baseball executive and promoter
- Pedro Morales (1942–2019), Puerto Rican professional wrestler
- Pedro Morales Flores (born 1985), Chilean football player
- Rags Morales, American comic book artist
- Ramón Morales (born 1975), Mexican professional footballer
- Dr. Ramón Villeda Morales (1908–1971), President of Honduras
- Rebecca Jo Morales (born 1962), American artist
- Ricardo Arjona Morales, Guatemalan song writer, music producer, poet, singer
- Ricardo Morales (born 1972), American musician
- Rodolfo Morales (1925–2001), Mexican artist
- Vina Morales (born 1975), Filipino singer and actor
- Virgilio Morales Díaz, Cuban Boy Scout leader
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- Cristóbal de Morales (c.1500–1553), Spanish composer
- Luis de Morales (c.1510–1586), Spanish painter
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- Gerardo Machado y Morales (1871–1939), Cuban politician
Fictional characters
- Morales, character in the television series The Walking Dead
- Jim Moralés, character in Code Lyoko (voiced by David Gasman)
- Enrique Morales, character in the HBO series Oz
- Lt. Morales, the combat medic, a playable character in the video game Heroes of the Storm
- Ramón Morales, character in the 2019 film Scary Stories to Tell in the Dark
- Miles Morales, Spider-Man in the Ultimate Comics: Spider-Man comic book series