Maceration may refer to:
- Maceration (food), in food preparation
- Maceration (wine), a step in wine-making
- Maceration (sewage), in sewage treatment
- Maceration (bone), a method of preparing bones
- Acid maceration, the use of an acid to extract micro-fossils from rock
- Maceration, in chemistry, the preparation of an extract by solvent extraction
- Maceration, in biology, the mechanical breakdown of ingested food into chyme
- Skin maceration, in dermatology, the softening and whitening of skin that is kept constantly wet
- Maceration, in poultry farming, a method of chick culling
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