Wikipedia

List of enzymes

This page lists enzymes by their classification in the International Union of Biochemistry and Molecular Biology's Enzyme Commission [EC] numbering system.

  • Category:EC 1.1.4 (with a disulfide as acceptor)

  • Category:EC 1.6.6 (with a nitrogenous group as acceptor)

  • Category:EC 1.8.6 deleted, included in EC 2.5.1.18

  • Category:EC 1.9.99 transferred, now EC 1.9.98.1

  • Cytochrome P450 oxidase

  • EC 2.8.1.1: Thiosulfate sulfurtransferase
  • EC 2.8.1.2: 3-mercaptopyruvate sulfurtransferase
  • EC 2.8.1.3: Thiosulfate--thiol sulfurtransferase
  • EC 2.8.1.4: tRNA uracil 4-sulfurtransferase
  • EC 2.8.1.5: Thiosulfate--dithiol sulfurtransferase
  • EC 2.8.1.6: Biotin synthase
  • EC 2.8.1.7: Cysteine desulfurase
  • EC 2.8.1.8: Lipoyl synthase
  • EC 2.8.1.9: Molybdenum cofactor sulfurtransferase
  • EC 2.8.1.10: Thiazole synthase
  • EC 2.8.1.11: Molybdopterin synthase sulfurtransferase
  • EC 2.8.1.12: Molybdopterin synthase
  • EC 2.8.1.13: tRNA-uridine 2-sulfurtransferase
  • EC 2.8.1.14: tRNA-5-taurinomethyluridine 2-sulfurtransferase
  • EC 2.8.1.15: tRNA-5-methyluridine(54) 2-sulfurtransferase

  • EC 2.9.1.1: L-seryl-tRNA(Sec) selenium transferase
  • EC 2.9.1.2: O-phospho-L-seryl-tRNA(Sec):L-selenocysteinyl-tRNA synthase

  • Hydrolytic enzyme

Amylase

Function: Amylase is an enzyme that is responsible for the breaking of the bonds in starches, polysaccharides, and complex carbohydrates to be turned into simple sugars that will be easier to absorb.

Clinical Significance: Amylase also has medical history in the use of Pancreatic Enzyme Replacement Therapy (PERT). One of the components is Sollpura (liprotamase), which help in the breakdown of saccharides into simple sugars.

Lysozyme

Function: An enzyme that is produced by animals that forms part of the innate immune system and is abundant in the secretions of saliva, human milk, tears, and mucus. It functions as an antimicrobial agent by splitting the peptidoglycan component of bacterial cell walls, which then leads to cell death.

Clinical Significance: Toxic levels of blood are caused by the excessive production of lysozyme's by cancer cells. Lysozyme's have also been associated with Bronchopulmonary dysplasia (BPD) in newborns and is a key factor in providing the immunology of infants during breast feeding.

Sucrase

Function: Sucrase is a stomachs related protein that mobilizes hydrolysis to convert sucrose into glucose and fructose.

Clinical Significance: Low amounts of Sucrose also known as Sucrose intolerance happens when sucrose isn’t being discharged in the small digestive tract. A result of this is extra gas.

Lactase

Function: lactase is located in the small digestives system of people and other creatures such as mammals. Lactase is the bases of the total absorption of milk.

Clinical Significance: People who are lactose intolerant have medicine that can help with the digestion. When you are lactose intolerant you might experience gas, bloating, and pain along with other symptoms regarding your digestive system.


  • Adenosylmethionine hydrolase
  • S-adenosyl-L-homocysteine hydrolase
  • Alkenylglycerophosphocholine hydrolase
  • Alkenylglycerophosphoethanolamine hydrolase
  • Cholesterol-5,6-oxide hydrolase
  • Hepoxilin-epoxide hydrolase
  • Isochorismatase
  • Leukotriene-A4 hydrolase
  • Limonene-1,2-epoxide hydrolase
  • Microsomal epoxide hydrolase
  • Trans-epoxysuccinate hydrolase

  • EC 3.8.1.3 Haloacetate dehalogenase

  • EC 3.9.1.1: Phosphoamidase
  • EC 3.9.1.2: Protein arginine phosphatase
  • EC 3.9.1.3: Phosphohistidine phosphatase

  • EC 3.10.1.1: N-sulfoglucosamine sulfohydrolase
  • EC 3.10.1.2: Cyclamate sulfohydrolase

  • EC 3.11.1.1: Phosphonoacetaldehyde hydrolase
  • EC 3.11.1.2: Phosphonoacetate hydrolase
  • EC 3.11.1.3: Phosphonopyruvate hydrolase

  • EC 3.13.1.1: UDP-sulfoquinovose synthase
  • EC 3.13.1.3: 2'-hydroxybiphenyl-2-sulfinate desulfinase
  • EC 3.13.1.4: 3-sulfinopropanoyl-CoA desulfinase
  • EC 3.13.1.5: Carbon disulfide hydrolase
  • EC 3.13.1.6: (CysO sulfur-carrier protein)-S-L-cysteine hydrolase
  • EC 3.13.1.7: Carbonyl sulfide hydrolase
  • EC 3.13.1.8: S-adenosyl-L-methionine hydrolase (adenosine-forming)

  • FKBP: FKBP1A
  • FKBP1B
  • FKBP2
  • FKBP3
  • FKBP4
  • FKBP5
  • FKBP6
  • FKBP8
  • FKBP9
  • FKBP10
  • FKBPL
  • Cyclophilin
  • Parvulin
  • Prolyl isomerase
  • 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase
  • Beta-carotene isomerase
  • Farnesol 2-isomerase
  • Furylfuramide isomerase
  • Linoleate isomerase
  • Maleate isomerase
  • Maleylacetoacetate isomerase
  • Maleylpyruvate isomerase
  • Parvulin
  • Photoisomerase
  • Prolycopene isomerase
  • Prolyl isomerase
  • Retinal isomerase
  • Retinol isomerase
  • Zeta-carotene isomerase

Intramolecular lyases:
EC number Examples
Muconate cycloisomerase
3-carboxy-cis,cis-muconate cycloisomerase
Tetrahydroxypteridine cycloisomerase
Inositol-3-phosphate synthase
Carboxy-cis,cis-muconate cyclase
Chalcone isomerase
Chloromuconate cycloisomerase
(+)-bornyl diphosphate synthase
Cycloeucalenol cycloisomerase
Alpha-pinene-oxide decyclase
Dichloromuconate cycloisomerase
Copalyl diphosphate synthase
Ent-copalyl diphosphate synthase
Syn-copalyl-diphosphate synthase
Terpentedienyl-diphosphate synthase
Halimadienyl-diphosphate synthase
(S)-beta-macrocarpene synthase
Lycopene epsilon-cyclase
Lycopene beta-cyclase
Prosolanapyrone-III cycloisomerase
D-ribose pyranase
EC 5.5.1.22 Steroid Delta Isomerase

6-carboxytetrahydropterin synthase

  • EC 6.2.1.1: Acetate--CoA ligase
  • EC 6.2.1.2: Medium-chain acyl-CoA ligase
  • EC 6.2.1.3: Long-chain-fatty-acid-CoA ligase
  • EC 6.2.1.4: Succinate-CoA ligase (GDP-forming)
  • EC 6.2.1.5: Succinate-CoA ligase (ADP-forming)
  • EC 6.2.1.6: Glutarate-CoA ligase
  • EC 6.2.1.7: Cholate-CoA ligase
  • EC 6.2.1.8: Oxalate-CoA ligase
  • EC 6.2.1.9: Malate-CoA ligase
  • EC 6.2.1.10: Acid-CoA ligase (GDP-forming)
  • EC 6.2.1.11: Biotin-CoA ligase
  • EC 6.2.1.12: 4-coumarate-CoA ligase
  • EC 6.2.1.13: Acetate-CoA ligase (ADP-forming)
  • EC 6.2.1.14: 6-carboxyhexanoate-CoA ligase
  • EC 6.2.1.15: Arachidonate-CoA ligase
  • EC 6.2.1.16: Acetoacetate-CoA ligase
  • EC 6.2.1.17: Propionate-CoA ligase
  • EC 6.2.1.18: Citrate-CoA ligase
  • EC 6.2.1.19: Long-chain-fatty-acid-luciferin-component ligase
  • EC 6.2.1.20: Long-chain-fatty-acid-(acyl-carrier-protein) ligase
  • EC 6.2.1.21: Transferred entry: 6.2.1.30
  • EC 6.2.1.22: (citrate (pro-3S)-lyase) ligase
  • EC 6.2.1.23: Dicarboxylate-CoA ligase
  • EC 6.2.1.24: Phytanate-CoA ligase
  • EC 6.2.1.25: Benzoate-CoA ligase
  • EC 6.2.1.26: o-succinylbenzoate-CoA ligase
  • EC 6.2.1.27: 4-hydroxybenzoate-CoA ligase
  • EC 6.2.1.28: 3a,7a-dihydroxy-5b-cholestanate-CoA ligase
  • EC 6.2.1.29: Transferred entry: 6.2.1.7
  • EC 6.2.1.30: Phenylacetate-CoA ligase
  • EC 6.2.1.31: 2-furoate-CoA ligase
  • EC 6.2.1.32: Anthranilate-CoA ligase
  • EC 6.2.1.33: 4-chlorobenzoate-CoA ligase
  • EC 6.2.1.34: Trans-feruloyl-CoA synthase
  • EC 6.2.1.35: ACP-SH:acetate ligase
  • EC 6.2.1.36: 3-hydroxypropionyl-CoA synthase
  • EC 6.2.1.37: 3-hydroxybenzoate—CoA ligase
  • EC 6.2.1.38: (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA synthase
  • EC 6.2.1.39: (butirosin acyl-carrier protein)—L-glutamate ligase
  • EC 6.2.1.40: 4-hydroxybutyrate-CoA ligase
  • EC 6.2.1.41: 3-((3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl)propanoate-CoA ligase
  • EC 6.2.1.42: 3-oxocholest-4-en-26-oate-CoA ligase
  • EC 6.2.1.43: 2-hydroxy-7-methoxy-5-methyl-1-naphthoate-CoA ligase
  • EC 6.2.1.44: 3-(methylthio)propionyl-CoA ligase
  • EC 6.2.1.45: E1 ubiquitin-activating enzyme
  • EC 6.2.1.46: L-allo-isoleucine--holo-CmaA peptidyl-carrier protein ligase
  • EC 6.2.1.47: Medium-chain-fatty-acid-(acyl-carrier-protein) ligase
  • EC 6.2.1.48: Carnitine-CoA ligase
  • EC 6.2.1.49: Long-chain fatty acid adenylyltransferase FadD28
  • EC 6.2.1.50: 4-hydroxybenzoate adenylyltransferase FadD22
  • EC 6.2.1.51: 4-hydroxyphenylalkanoate adenylyltransferase FadD29
  • EC 6.2.1.52: L-firefly luciferin-CoA ligase
  • EC 6.2.1.53: L-proline-L-prolyl-carrier protein ligase
  • EC 6.2.1.54: D-alanine-D-alanyl-carrier protein ligase
  • EC 6.2.1.55: E1 SAMP-activating enzyme

DNA ligase (EC 6.5.1.1)

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