Lewis and Clark collectively refers to Meriwether Lewis and William Clark, leaders of the Lewis and Clark Expedition, the first expedition to cross the western portion of the United States.
Lewis and Clark or Lewis & Clark may also refer to:
Places
- Lewis and Clark Caverns, limestone caverns and associated sites in Montana
- Lewis and Clark County, Montana
- Lewis and Clark National Forest in central Montana
- Lewis and Clark National Historical Park, a collection of state and federal sites near Astoria, Oregon
- Lewis and Clark National Historic Trail, a trail from Illinois to Oregon
- Lewis and Clark River, a river in northwest Oregon
- Lewis and Clark State Historic Site, a historic site in Hartford, Illinois
- Lewis and Clark State Recreation Site, a state park near Troutdale, Oregon
Other uses
- Lewis & Clark (elm cultivar)
- Lewis and Clark (sculpture), a 1934 sculpture by Leo Friedlander
- Lewis & Clark (TV series), a short-lived NBC series
- Lewis & Clark: The Journey of the Corps of Discovery, a 1997 documentary film by Ken Burns
- USNS Lewis and Clark (T-AKE-1), a support ship of the US Navy
- Lewis and Clark-class dry cargo ship
- Lewis and Clark Centennial Exposition, an exposition in Portland, Oregon
- Lewis & Clark College, a private college in Portland, Oregon
- Lewis and Clark Community College, a community college in Godfrey, Illinois
See also
- Lewis and Clark Bridge (disambiguation)
- Lewis and Clark Highway (disambiguation)
- Lewis & Clarke, the nom-de-plume of musician Lou Rogai
- Lois & Clark: The New Adventures of Superman, a 1990s Superman television series
- Luis and Clark, a line of carbon-fiber stringed instruments