Ike or IKE may refer to:
People
- Ike (given name), a list of people with the name or nickname
- Dwight D. Eisenhower (1890-1969), Supreme Commander of the Allied forces in Europe during World War II and President of the United States
Surname
- Ike no Taiga (1723–1776), Japanese painter
- Chika Ike (born 1985), Nigerian actress
- Ike Gyokuran (1727–1784), Japanese painter
- Reiko Ike (born 1953), Japanese actress
Storms
- Severe tropical storm Ike (Bining), in the 1981 Pacific typhoon season
- Typhoon Ike (Nitang), in the 1984 Pacific typhoon season
- Hurricane Ike (2008), in Greater Antilles and Northern America
Arts and entertainment
- Ike (miniseries), a 1979 television miniseries about Eisenhower
- Ike: Countdown to D-Day, a 2004 American television film
- Ike, a fictional moon in the game Kerbal Space Program
Transportation and military
- Ikerasak Heliport (LID airport code), Greenland
- USS Dwight D. Eisenhower, an aircraft carrier
- Dwight D. Eisenhower Expressway, part of Interstate 290
Other uses
- Internet Key Exchange, a network protocol used by IPsec VPNs
- IKE Group, economic research group at Aalborg University, Denmark
- Ike, Texas, an unincorporated community in the US
- Inuktitut (ISO 639-3 code: ike), an Inuit language of Canada
- Ike (Fire Emblem), one of the main characters from the Fire Emblem game series