Erythrose 4-phosphate

Erythrose 4-phosphate

Names
Other names E4P
Identifiers
CAS Number	585-18-2
3D model (JSmol)	Interactive image
ChEBI	CHEBI:48153
ChemSpider	4573609
MeSH	erythrose+4-phosphate
PubChem CID	5459862
UNII	2156QF7O8M
InChI InChI=1S/C4H9O7P/c5-1-3(6)4(7)2-11-12(8,9)10/h1,3-4,6-7H,2H2,(H2,8,9,10)/p-2/t3-,4+/m0/s1 Key: NGHMDNPXVRFFGS-IUYQGCFVSA-L InChI=1/C4H9O7P/c5-1-3(6)4(7)2-11-12(8,9)10/h1,3-4,6-7H,2H2,(H2,8,9,10)/p-2/t3-,4+/m0/s1 Key: NGHMDNPXVRFFGS-VVTNXMPSBK
SMILES [O-]P([O-])(=O)OC[C@@H](O)[C@@H](O)C=O
Properties
Chemical formula	C4H9O7P
Molar mass	200.084 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Erythrose 4-phosphate is a phosphate of the simple sugar erythrose. It is an intermediate in the pentose phosphate pathway and the Calvin cycle.^[1]

In addition, it serves as a precursor in the biosynthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. It is used in the first step of the shikimate pathway. At this stage, phosphoenolpyruvate and erythrose-4-phosphate react to form 3-deoxy-D-arabinoheptulosonate-7-phosphate (DAHP), in a reaction catalyzed by the enzyme DAHP synthase.

Biosynthesis of DAHP from phosphoenolpyruvate and erythrose-4-phosphate

It also used in 3-hydroxy-1-aminoacetone phosphate biosynthesis, which is a precursor of vitamin B6 in DXP-dependent pathway. Erythrose-4-phosphate dehydrogenase is used to produce erythronate-4-phosphate.

References