DDS may refer to:
- Doctor of Dental Surgery, academic degree for dentists
- De Danske Skytteforeninger, founded in 1862 and was Denmark's oldest sports organization until the merger with the Danish Gymnastics and Sports Associations in 2013
Computer and information science
- Data Design System, DDS-CAD software vendor
- Direct Digital Synthesis, a method for the generation of periodic digital signals
- Data Definition Specification, in software data management
- Data Description Specifications, in AS/400 programming
- Data Distribution Service, an Object Management Group standard for publish/subscribe middleware for distributed systems
- Data dictionary system of ICL's VME operating system; see ICL VME#QuickBuild
- Digital Data Storage, a storage tape format related to Digital Audio Tape (DAT)
- DirectDraw Surface, .dds texture files
- Donovan Data Systems, software & computer services company
- Dynamic digital signage
- Leased line, Dataphone Digital Service or Digital Data System
Electronics and communications
- Direct digital synthesizer, a type of frequency synthesizer used for creating arbitrary waveforms from a single, fixed-frequency reference clock
Chemistry
- Dimethyldichlorosilane, an organosilicon compound
- Dammarenediol II synthase, an enzyme
Law and administration
- Disability Determination Service, a state agency in the United States that determines eligibility for federal disability benefits
- Department of Driver Services, also known as Department of Motor Vehicles
Healthcare
- Dapsone, also known as diaminodiphenyl sulfone (DDS), an antibiotic commonly used for the treatment of leprosy
- Doctor of Dental Surgery, an academic degree
- Dopamine dysregulation syndrome, a condition connected with treatment for Parkinson's disease
- Drug delivery systems, how drugs are delivered to relevant areas or tissues
Arts and popular culture
- Digimon Data Squad, season 5 of the Digimon anime
- Shin Megami Tensei: Digital Devil Saga, a 2004 video game spun off from the Shin Megami Tensei series
- Dmitri Dmitriyevich Shostakovich, Russian composer
Schools
- Dutchess Day School, private Pre-K through 8th Grade School in Millbrook, New York, United States
- Davidson Day School, Pre-K through 12th Grade School in Davidson, North Carolina, United Statesd
Other uses
- Diehard Duterte Supporters, a term used for staunch supporters of Rodrigo Duterte, the 16th President of the Philippines
- Davao Death Squad, a vigilante group in Davao City, Philippines
- Deflation Detection System
- Dewey Decimal Classification, often called the Dewey Decimal System
- Dry deck shelter, a removable module that can be attached to a submarine to allow divers easy exit and entrance while the submarine is submerged
- Dark dune spot, a feature of the Martian landscape
- Direct Delivery Scheme, of the Society of Independent Brewers