Charles Mitchell may refer to:
- Charles Mitchell (footballer), British soccer player
- Charles Mitchell (academic) (born 1965), professor of law at University College, London
- Charles Mitchell (American football) (born 1989), American football player
- Charles Mitchell (basketball) (born 1993), American basketball player
- Charles Mitchell (colonial administrator) (1836–1899), colonial administrator in the British Colonial Service
- Charles Mitchell (shipbuilder) (1820–1895), British shipbuilder
- Charles Mitchell (songwriter), American songwriter of the 1930s and 1940s
- Charles Mitchell (c. 1848–1876?), mulatto slave, owned by James Tilton, who escaped from the Washington Territory to the British Crown Colony of Victoria in 1860
- Charles Bayard Mitchell (1857–1942), American bishop of the Methodist Episcopal Church
- Charles E. Mitchell (1877–1955), American banker
- Charles F. Mitchell (1806–1865), U.S. Representative from New York
- Charles Le Moyne Mitchell (1844–1890), U.S. Representative from Connecticut
- Charles Louis Mitchell (1859–1918), Scottish artist
- Charles Richmond Mitchell (1872–1942), Canadian lawyer, judge, cabinet minister in Alberta
- Charles S. Mitchell (1856–1922), American newspaper publisher and editor
- Charles William Mitchell (1854–1903), English pre-Raphaelite painter
- Charlie Mitchell (born 1962), baseball player
- Charlie Mitchell (American football) (1920–1999), defensive back in the National Football League
- Charlie Mitchell (footballer) (born 1948), Scottish American former soccer defender and coach
- Chuck Mitchell (1927–1992), American actor
- Mitch Mitchell (guitarist) (Charles Mitchell III, born 1959), musician and former member of Guided by Voices
- C. Ainsworth Mitchell (1867–1948), English chemist and forensic scientist
- Charles H. Mitchell (born 1940), American academic administrator and American football player
See also
- Charles Mitchel (disambiguation)
- Charles Mitchell Whiteside (1854–1924), American politician and businessman