Bubble boy, boy in the bubble or boy in the plastic bubble may refer to:
Diseases
- Severe combined immunodeficiency, sometimes called 'bubble boy disease', a genetic disorder which results in an extreme vulnerability to infectious diseases
Patients
- Ted DeVita (1962–1980), victim of severe aplastic anaemia who was forced to live in a sterile hospital room
- David Vetter (1971–1984), victim of severe combined immune deficiency syndrome who was forced to live in a sterile environment
Books, movies etc. inspired by the patients' lives
- The Boy in the Plastic Bubble, a 1976 film starring John Travolta
- The Boy in the Bubble, a British children's novel by Ian Strachan, winner of the 1994 Red House Children's Book Award
- "The Bubble Boy" (Seinfeld), a 1992 episode of the Seinfeld TV series
- Bubble Boy (film), a 2001 film starring Jake Gyllenhaal
- Bubble Boy (musical), a 2008 musical based on the film
Other uses
- "Bubble Boy", an episode of The Powerpuff Girls
- "The Boy in the Bubble", a 1986 song by Paul Simon from the album Graceland